{"id":1547,"date":"2020-07-22T12:53:11","date_gmt":"2020-07-22T10:53:11","guid":{"rendered":"https:\/\/dev.l7labs.de\/l7sitedev\/web\/?p=1547"},"modified":"2020-10-12T22:14:09","modified_gmt":"2020-10-12T20:14:09","slug":"bacterial-co-infection-and-secondary-infection-in-patients-with-covid-19","status":"publish","type":"post","link":"https:\/\/dev.l7labs.de\/l7sitedev\/web\/bacterial-co-infection-and-secondary-infection-in-patients-with-covid-19\/","title":{"rendered":"Bacterial co-infection and secondary infection in patients with COVID-19"},"content":{"rendered":"[vc_row type=”in_container” full_screen_row_position=”middle” column_margin=”default” scene_position=”center” text_color=”dark” text_align=”left” overlay_strength=”0.3″ shape_divider_position=”bottom” bg_image_animation=”none”][vc_column column_padding=”no-extra-padding” column_padding_position=”all” background_color_opacity=”1″ background_hover_color_opacity=”1″ column_link_target=”_self” column_shadow=”none” column_border_radius=”none” width=”1\/12″ tablet_width_inherit=”default” tablet_text_alignment=”default” phone_text_alignment=”default” overlay_strength=”0.3″ column_border_width=”none” column_border_style=”solid” bg_image_animation=”none”][\/vc_column][vc_column column_padding=”no-extra-padding” column_padding_position=”all” background_color_opacity=”1″ background_hover_color_opacity=”1″ column_link_target=”_self” column_shadow=”none” column_border_radius=”none” width=”5\/6″ tablet_width_inherit=”default” tablet_text_alignment=”default” phone_text_alignment=”default” overlay_strength=”0.3″ column_border_width=”none” column_border_style=”solid” bg_image_animation=”none”][vc_column_text]\n
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Background:\u00a0<\/strong>Bacterial co-pathogens are commonly identified in viral respiratory infections and are important causes of morbidity and mortality. The prevalence of bacterial infection in patients infected with SARS-CoV-2 is not well understood.<\/p>\n

Aims:\u00a0<\/strong>To determine the prevalence of bacterial co-infection (at presentation) and secondary infection (after presentation) in patients with COVID-19.<\/p>\n

Sources:\u00a0<\/strong>We performed a systematic search of MEDLINE, OVID Epub and EMBASE databases for English language literature from 2019 to April 16, 2020. Studies were included if they (a) evaluated patients with confirmed COVID-19 and (b) reported the prevalence of acute bacterial infection.<\/p>\n

Content:\u00a0<\/strong>Data were extracted by a single reviewer and cross-checked by a second reviewer. The main outcome was the proportion of COVID-19 patients with an acute bacterial infection. Any bacteria detected from non-respiratory-tract or non-bloodstream sources were excluded. Of 1308 studies screened, 24 were eligible and included in the rapid review representing 3338 patients with COVID-19 evaluated for acute bacterial infection. In the meta-analysis, bacterial co-infection (estimated on presentation) was identified in 3.5% of patients (95%CI 0.4-6.7%) and secondary bacterial infection in 14.3% of patients (95%CI 9.6-18.9%). The overall proportion of COVID-19 patients with bacterial infection was 6.9% (95%CI 4.3-9.5%). Bacterial infection was more common in critically ill patients (8.1%, 95%CI 2.3-13.8%). The majority of patients with COVID-19 received antibiotics (71.9%, 95%CI 56.1 to 87.7%).<\/p>\n

Implications:\u00a0<\/strong>Bacterial co-infection is relatively infrequent in hospitalized patients with COVID-19. The majority of these patients may not require empirical antibacterial treatment.<\/p>\n

Keywords:\u00a0<\/strong>Bacterial infections; COVID-19; Co-infection; Living review; Secondary infection.<\/p>\n<\/div>\n<\/div>\n

Crown Copyright \u00a9 2020. Published by Elsevier Ltd. All rights reserved.<\/p>\n[\/vc_column_text][divider line_type=”No Line” custom_height=”20″][nectar_cta btn_style=”arrow-animation” heading_tag=”h4″ text_color=”#282e33″ button_color=”default” link_type=”new_tab” alignment=”left” display=”block” link_text=”Read Full Article on pubmed.gov” url=”https:\/\/pubmed.ncbi.nlm.nih.gov\/32711058\/”][\/vc_column][vc_column column_padding=”no-extra-padding” column_padding_position=”all” background_color_opacity=”1″ background_hover_color_opacity=”1″ column_link_target=”_self” column_shadow=”none” column_border_radius=”none” width=”1\/12″ tablet_width_inherit=”default” tablet_text_alignment=”default” phone_text_alignment=”default” overlay_strength=”0.3″ column_border_width=”none” column_border_style=”solid” bg_image_animation=”none”][\/vc_column][\/vc_row]\n","protected":false},"excerpt":{"rendered":"

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